VST noises when monitoring (Reaper + Pure Data + LoopMIDI/LoopBe1)

Hello I am using Vital VST in Reaper getting midi input from Pure Data through LoopMIDI (or LoopBe1, I am having the same issue), on Windows 11.

When I record an audio waveform (not a midi item), I have a lot of noise just in monitoring when I send a lot of data from Pure Data. I think it should be something about buffering or similar…
Did anyone have the same issue?